Staff

Curriculum Vitae Tina Oberacker

Affiliation

Scientist at the Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart and University of Tübingen

Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology
Auerbachstr. 112
D-70376 Stuttgart
phone: ++49-711-8101 2833
fax: ++49-711-859295
email: tina.oberacker@rbk.de

Dr. rer. nat. Tina Oberacker

++49-711-8101 2833

Tina Oberacker

Education and Professional Career

2001-2006	Studies in Biology at the University of Karlsruhe (TH), Karlsruhe, Germany
2006	Diploma thesis in Zoological Institute, Department of Cell- and Neurobiology at the University of Karlsruhe, Karlsruhe, Germany “Biochemische Charakterisierung chimärer TRP- und TRPL-Kanäle aus den Komplexaugen transgener Drosphila melanogaster“ (Prof. R. Paulsen)
2007-2011	PhD thesis in the Institute of Physiology, Department of Biosensorics at the University of Hohenheim, Stuttgart, Germany (Prof. A. Huber) “Funktion N- und C-terminaler Proteindomänen für Assemblierung, subzelluläre Lokalisation und Physiologie der TRP-Ionenkanäle in Drosophila Photorezeptoren”
2011-2013	Scientist at the Institute of Physiology, Department of Biosensorics at the University of Hohenheim, Stuttgart, Germany (Prof. A. Huber)
2013-2018	Scientist at the German Cancer Research Center (DKFZ), Tumor Immunology Program (D030), Heidelberg, Germany (Prof. P.H. Krammer)
since 2019	Scientist at the Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology

Selected References

Schricker S, Oberacker T, Fritz P, Ketteler M, Alscher MD, Schanz M, “Peritoneal Expression of SGLT-2, GLUT1, and GLUT3 in Peritoneal Dialysis Patients.”, Kidney Blood Press Res. 2022;47(2):125-134. doi: 10.1159/000520894.

Schanz M, Schöffski O, Kimmel M, Oberacker T, Göbel N, Franke UFW, Alscher MD, Ketteler M, Schricker S., “Under-recognition of Acute Kidney Injury after Cardiac Surgery in the ICU Impedes Early Detection and Prevention.”, Kidney Blood Press Res. 2022;47(1):50-60. doi: 10.1159/000519536.

Oberacker T, Bajorat J, Ziola S, Schroeder A, Röth D, Kastl L, Edgar BA, Wagner W, Gülow K, Krammer PH., “Enhanced expression of thioredoxin-interacting-protein regulates oxidative DNA damage and aging.”, FEBS Lett. 2018 Jul;592(13):2297-2307. doi: 10.1002/1873-3468.13156.

Schroeder A, Warnken U, Röth D, Klika KD, Vobis D, Barnert A, Bujupi F, Oberacker T, Schnölzer M, Nicolay JP, Krammer PH, Gülow K. “Targeting Thioredoxin-1 by dimethyl fumarate induces ripoptosome-mediated cell death.”, Sci Rep. 2017 Feb 24;7:43168. doi: 10.1038/srep43168

Bajorat J, Oberacker T, Ziola S, Edgar BA, Gülow K, Krammer PH., “AF-1 a novel regulator of the redox equilibrium during aging.”, Free Radic Biol Med. 2014 Oct;75 Suppl 1:S22-3. doi: 10.1016/j.freeradbiomed.2014.10.737

Katz B, Oberacker T, Richter D, Tzadok H, Peters M, Minke B, Huber A., „Drosophila TRP and TRPL are assembled as homomultimeric channels in vivo.”, J Cell Sci. 2013 Jul 15;126(Pt 14):3121-33. doi: 10.1242/jcs.123505.

Richter D, Katz B, Oberacker T, Tzarfaty V, Belusic G, Minke B, Huber A., „Translocation of the Drosophila transient receptor potential-like (TRPL) channel requires both the N- and C-terminal regions together with sustained Ca2+ entry.”, J Biol Chem. 2011 Sep 30;286(39):34234-43. doi: 10.1074/jbc.M111.278564

Cerny AC, Oberacker T, Pfannstiel J, Weigold S, Will C, Huber A., “Mutation of light-dependent phosphorylation sites of the Drosophila transient receptor potential-like (TRPL) ion channel affects its subcellular localization and stability.”, J Biol Chem. 2013 May 31;288(22):15600-13. doi: 10.1074/jbc.M112.426981

Major Projects

Biobank “Peritonealdialyse) S569-PD, RBK
peritoneal membrane integrity
identification of deliverable drugs for treatment of PD patients in clinical practice
establishment of a directional peritoneal model