Education

Our teaching programs

Buch1

PhD Curriculum in cooperation with the University Tuebingen

18.10.2023  S. Johnsen (RBCT)                   Molecular cancer epigenetics
08.11.2023F. Essmann (RBCT)Apoptosis regulation and targeted therapy
22.11.2023V. Lauschke    Microphysiological tissue models
06.12.2023R. Kosinsky (RBCT)Inflammation-driven tumorigenesis
13.12.2023A. Nies / O. BurkTransport & nuclear receptors
10.01.2024T. Mürdter / M. DongTumor models & microenvironment 
24.01.2024Z. Najafova (RBCT)Tumor cell plasticity
14.02.2024H. Cramer (RCM)             Research Complementary Medicine
28.02.2024E. Schäffeler / M. Schwab / F. Büttner        Integrative omics analyses & cancer therapy

 

26.04.2023  A. Nies                   Using mouse models to understand human physiology and disease
03.05.2023U. HofmannAnalytical concepts and methods in clinical pharmacology
10.05.2023F. Essmann (RBCT)     Flow cytometry and cellular imaging
17.05.2023K. KleinThe human genome, RNAi and editing
14.06.2023M. Ueffing (TÜ)Proteomics – From basic approaches to clinical applications
28.06.2023K. KleinAnalysis of DNA variation 
12.07.2023R. TremmelPGx and biomarkers
19.07.2023S. Winter               Basic statistics for GWAS
26.07.2023M. HaagMetabolomics – technology and application

 

19.10.2022  H. Brauch                   How to write a paper, scientific publishing
16.11.2022 S. JägerClinical studies – design and realization
23.11.2022M. van der Lee (Univ. Leiden, NL)     Long-read sequencing and AI in pharmacogenomics
30.11.2022A. Bräuning (BfR)Food safety at the German Federal Institute for Risk Assessment
14.12.2022S. RüdesheimDrug-drug-gene interactions and PBPK modeling
11.01.2023S. WinterIntroduction to statistical analyses  
18.01.2023A. NiesPharmacogenomics of drug transporters
25.01.2023A. Maßmann (RBK)               Standard and advanced clinical imaging
08.02.2023F. BüttnerApplied bioinformatics

 

20.04.2022  M. Schwab                   Physiological specialties in children
27.04.2022 A. Hartkopf (Ulm)Physiology and pathophysiology of the breast
04.05.2022P. Ong / A. HubertPhysiology and pathophysiology of the cardiovascular system
25.05.2022K. Rapp    Grundbegriffe der Geriatrie einschließlich besonderer Aspekte der Pharmakotherapie bei gebrechlichen Menschen
02.06.2022C. NeurohrPhysiology and pathophysiology of the lung
15.06.2022S. JohnsenGenetic and Epigenetic Regulation of Pancreatic Cancer-Development and Progression    
29.06.2022M.H. DahlkePeritoneal metastasis
13.07.2022N. Lubomierski                Drug therapy of diabetes, obesity, metabolic syndrome
27.07.2022V. LauschkeMicrophysiological tissue systems to study drug response

 

20.10.2021       F. Essmann                         Welcome and Introduction
27.10.2021  U. ZangerThe human genome – an overview Enzymes
10.11.2021O. BurkTranscriptional regulation of gene expression
24.11.2021H. Horn, A. Staiger, F. Herster     Molecular pathology & molecular tumor board
08.12.2021O. Rieß (TÜ)Diagnostics of rare diseases: beyond the exome
22.12.2021W. SchrothPharmacogenomics and precision medicine (breast cancer)     
12.01.2022R. HoppeEpigenetics and cancer
26.01.2022M. Ketteler                     Physiology and pathophysiology of the kidneys
09.02.2022tbaKidneys and cancer

 

31.03.2021       F. Essmann                         Welcome and Introduction / Basic Immunology
14.04.2021  U. ZangerDrug Metabolism and Drug Metabolizing Enzymes
28.04.2021O. BurkDrug Metabolism & Transport, Nuclear Receptors
05.05.2021A. NiesBiochemistry & Pharmacology of Drug Transport
19.05.2021M. SchwabPharmacogenetics and –genomics
02.06.2021T. MürdterBreast Cancer / Tamoxifen
16.06.2021F. Albert (RBK)Physiology  and  pathophysiology of the gastrointestinal  tract      
30.06.2021C. Schäfer (RBK)                     Physiology and pathophysiology of the liver
21.07.2021F. EssmannFood intake and digestion

Molecular Medicine for Biologists in cooperation with the University Hohenheim

Course “Molecular Medicine for Biologists” at the University of Hohenheim in cooperation with the IKP/RBK;
Responsible for the module: Prof. Steffen Lemke (University Hohenheim) and Dr. Oliver Burk/PD Dr. Frank Essman (IKP)
LV-Code: 1926-270

Venue:
Robert Bosch Hospital (RBK), Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology (IKP), Auerbachstr. 112, 70376 Stuttgart


Part 1:  Theoretical Basics, lectures and introduction (12,5 hours) 
04.03.2024-08.03.2024
(Library of the IKP, 2nd basement)

Lecturers and content:
Monday, 04.03.2024
 
9:30 hrs
 
Dr. Oliver Burk (0,5 hrs):
Group assignment/ Organisation and instruction in "safe working in the laboratory"
 10:30 hrs     
 
Dr. Roman Tremmel (2 hrs):
Overview of research at the IKP and Basics of “clinical pharmacology”
Tuesday, 05.03.2024
 
10:00 hrs
 
Dr. Heike Horn (2 hrs):
Overview of research at the RBK and Basics of "malignant transformation"
Wednesday, 06.03.2024      
 
10:00 hrs
 
PD Dr. Frank Essmann (1,5 hrs), Dr. Thomas Mürdter (1,5 hrs):
Introduction to practical exercises
Thursday, 07.03.2024
 
10:00 hrs
 
Dr. Oliver Burk (2,5 hrs):
Introduction to practical exercises
Friday, 08.03.2024
 
10:00 hrs
 
Dr. Roman Tremmel (1,5 hrs), Dr. Thomas Mürdter (1 hr):
Introduction to practical exercises and "Evaluation and presentation of scientific experiments"

Part 2:  Practical exercises and colloquia (30 hrs)
11.03.2024‑15.03.2024, 9:15-12:00 and 13:00-15:30 (Laboratories of the IKP) in total 30 hours
Each practical part starts with a 10min colloquium

Lecturers and content: 
Dr. Roman Tremmel:Molecular biological techniques, genotyping, etc.
PD Dr. Frank Essmann:       Cellular model systems to study the effects of antitumor drugs
Dr. Oliver Burk: Drugs as ligands of xenobiotic-activated nuclear receptors: cell-based assay systems: Transfection and reporter gene assays
Dr. Thomas Mürdter: In vitro investigation of drug metabolism and transport by HPLC

Part 3:  Debriefing  (3,5 hrs)
18.03.2024, 9:30-12:15 ((Library of the IKP, 2nd basement)
Submission of record: 02.04.2024


Literature

 

Course “Molecular Medicine for Biologists” at the University of Hohenheim in cooperation with the IKP/RBK;
Responsible for the module: Prof. Dr. Blum and Dr. Oliver Burk/PD Dr. Frank Essman
LV-Code: 2201-270

Venue:
Robert Bosch Hospital (RBK), Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology (IKP), Auerbachstr. 112, 70376 Stuttgart


Part 1:  Theoretical Basics, lectures and introduction (12,5 hours) 
06.03.2023-10.03.2023
(Library of the IKP, 2nd basement)

Lecturers and content:
Monday, 06.03.2023
 
9:30 hrs
 
Dr. Oliver Burk (0,5 hrs):
Group assignment/ Organisation and instruction in "safe working in the laboratory"
 10:30 hrs     
 
Prof. Dr. Walter Aulitzky (2 hrs):
Overview of research at the RBK and Basics of “malignant transformation”
Tuesday, 07.03.2023
 
10:00 hrs
 
Dr. Roman Tremmel (1,5 hrs), Dr. Thomas Mürdter  (1,5 hrs):
Introduction to practical exercises
Wednesday, 08.03.2023      
 
10:00 hrs
 
Dr. Oliver Burk (2,5 hrs):
Introduction to practical exercises
Thursday, 09.03.2023
 
10:00 hrs
 
PD Dr. Frank Essmann (1,5 hrs), Dr. Thomas Mürdter (1 hrs):
Introduction to practical exercises and "Evaluation and presentation of scientific experiments"
Friday, 10.03.2023
 
10:00 hrs
 
Prof. Dr. Matthias Schwab, Dr. Heike Horn (2 hrs):
Overview of research at the IKP and Basics of “Clinical Pharmacology”

Part 2:  Practical exercises and colloquia (30 hrs)
13.03.2023‑17.03.2023, 9:15-12:00 and 12:45-15:30 (Laboratory of the IKP) in total 30 hours
Each practical part starts with a 10min colloquium

Lecturers and content: 
Dr. Roman Tremmel:Molecular biological techniques, genotyping, etc.
PD Dr. Frank Essmann:       Cellular model systems to study the effects of antitumor drugs
Dr. Oliver Burk: Drugs as ligands of nuclear receptors: cell-based assay systems: Transfection and reporter gene assays
Dr. Thomas Mürdter: In vitro investigation of drug metabolism and transport by HPLC
Dr. Heike Horn:Molecular pathology and diagnostics

Part 3:  Debriefing  (3,5 hrs)
20.03.2023, 9:30-12:15 ((Library of the IKP, 2nd basement)
Submission of record: 06.04.2023


Literature

 

Invited Lectures

25.01.2023    

Prof. Dr. Jörn Lausen ,  University of Stuttgart
Gene expression control in differentiation and disease

22.02.2023    

Prof. Dr. Gustav Dobos ,  Center for Naturopathy and Integrative Medicine at the University Hospital Essen
Planetary Health Diet: Healthy eating for people and planet. What is the evidence?

29.03.2023    

Prof. Dr. André F. Martins ,  Full Professor in Advanced Preclinical Metabolic Imaging and Cell Engineering, University Hospital Tübingen
Harnessing metabolic imaging to monitor cancer aggressiveness non-invasively in vivo

26.04.2023    

PD Dr. Daniel Lipka ,  National Center for Tumor Diseases (NCT) Heidelberg & German Cancer Research Center (DKFZ)
RAS Pathway Mutations Drive Onco Fetal Reprogramming in Juvenile Myelomonocytic Leukemia

10.05.2023    

PD Dr. Frank Essmann ,  Robert Bosch Center for Tumor Diseases (RBCT) , Stuttgart
Flow cytometry and cellular imaging

14.06.2023       

Prof. Marius Ueffing , Institute for Ophthalmic Research, University Hospital Tübingen
Proteomics – From basic approaches to clinical applications

28.06.2023       

Prof. Dr. Verena Labi , Institute of Developmental Immunolog,y Medical University of Innsbruck
Roles of epigenetic TET enzymes in hematologic cancers and immunity

06.07.2023    

Sophia Steinlein ,  Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology , Stuttgart
Lymphoma associated stromal cells as an innovative therapeutic target for diffuse large B cell lymphoma

13.07.2023       

Sabrina Kalmbach , Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart
Novel insights into the pathogenesis of follicular lymphoma by molecular profiling of localized and systemic disease forms

20.09.2023       

Joanna Aggrey Fynn , Robert Bosch Center for Tumor Diseases (RBCT) , Stuttgart
Regulation of Pancreatic Cancer Metastasis by Signal Conversion in the Epigenome

27.09.2023       

Prof. Dr. Sonja Loges , Medical Faculty Mannheim, Heidelberg University
Precision Oncology - from bench to bedside

28.09.2023       

Dr. Jeremy Y. Ng , Centre for Journalology , Ottawa Methods Centre, Ottawa Hospital Research Institute, Ottawa, Canada
Basic Principles in Scholarly Publishing and Open Science Practices: A Primer

11.10.2023       

Tobias Beigl , Robert Bosch Center for Tumor Diseases (RBCT) , Stuttgart
Novel insights into the transmembrane domain interactome of Bcl 2 proteins elucidated by a bimolecular split luciferase assay and it’s impact on apoptosis signalling

18.10.2023       

Prof. Dr. Steven Johnsen , Robert Bosch Center for Tumor Diseases (RBCT) , Stuttgart
Molecular cancer epigenetics

08.11.2023       

PD Dr. Frank Essmann , Robert Bosch Center for Tumor Diseases (RBCT) , Stuttgart
Apoptosis regulation and targeted therapy

15.11.2023       

Julia Thiel , Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart
Patient-derived precision-cut tumor slices as a tool to study CD3-bispecific antibody therapy in solid tumors

29.11.2023       

Prof. Dr. Lisa Maier , Interfaculty Institute of Microbiology and Infection Medicine, University of Tübingen
The consequences of drugging the gut microbiome –from the individual microbe to the host

06.12.2023       

Thomas Ekstrom , Robert Bosch Center for Tumor Diseases (RBCT) , Stuttgart
Lineage defining transcription factors regulate PDAC subtype identity through distinct mechanisms

06.12.2023       

PD Dr. Robyn Laura Kosinsky , Adj. Assis.Prof. for Medicine at Mayo Clinic, Robert Bosch Center for Tumor Diseases (RBCT)
Inflammation driven tumorigenesis

 

13.01.2022       

Svenja Wallisch, Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart
FORGI: Fibroblast tumor ORGanoids Immune cell co-culture – a new model to understand tumor microenvironment interactions

26.01.2022      

Prof. Markus Ketteler, MD, Robert Bosch Hospital, Stuttgart
Physiology and pathophysiology of the kidneys

27.01.2022      

Jing Yang, Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart
Research the function of hOCT1 in Drosophila melanogaster expressing hOCT1 by feeding cisplatin and cimetidine

17.02.2022      

Marcel Lackner , Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart
Establishment of Stable Isotope resolved Metabolomics as Test System to assess Membrane associated Drug Targets in Cancer

07.04.2022      

Charlotte Kölz , Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart
Functional characterization of the two liver transporters OAT2 and OAT7 through in vitro methods and two novel mouse models

27.04.2022   

Prof. Andreas Hartkopf, MD, Clinic for Gynecology and Obstetrics at the University Hospital Ulm
Physiology and pathophysiology of the breast 

28.04.2022      

Simeon Rüdesheim , Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart
Physiologically Based Pharmacokinetic Modeling to Describe and Predict the Activity Score-Dependent Metabolism of CYP2D6 Substrates

04.05.2022   

Prof. Peter Ong, MD, and Astrid Hubert, MD, Robert Bosch Hospital, Stuttgart
Physiology and pathophysiology of the cardiovascular System

12.05.2022      

Benjamin Schäfer , Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart
Potential of BCL2 Inhibition in Ovarian Cancer Therapy

19.05.2022      

Sandra Weller , Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart
ABT-199 synergizes with PI via transactivation of NOXA

25.05.2022   

Prof. Kilian Rapp, MD, Robert Bosch Hospital, Stuttgart
Grundbegriffe der Geriatrie einschließlich besonderer Aspekte der Pharmakotherapie bei gebrechlichen Menschen 

02.06.2022   

Prof. Claus Neurohr, MD, RBK Lung Center Stuttgart, Clinic Schillerhöhe GmbH
Physiology and pathophysiology of the lung

15.06.2022   

Robyn Laura Kosinsky, PhD, Robert Bosch Center of  Tumor Diseases, Stuttgart
Intestinal inflammation and tumorigenesis –Pathogenesis, molecular classification and experimental tools

23.06.2022      

Christina Schräpel , Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart
Physiologically Based Pharmacokinetic (PBPK) Modeling of Enclomiphene and its Metabolites Predicting Drug Drug Gene Interaction (DDGI) Scenarios

29.06.2022   

Prof. Marc Dahlke, MD, Robert Bosch Hospital, Stuttgart
Metastatic Disease from a Surgeons Perspective 

07.07.2022      

Tobias Beigl , Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart
Brought to light: The interaction pattern of Bcl-2 transmembrane domains in a bimolecular luciferase complementation assay

13.07.2022   

Nikolaus Lubomierski, MD, Robert Bosch Hospital, Stuttgart
Novel Classification and Treatment of Diabetes Mellitus

14.07.2022      

Sophia Steinlein , Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart
Lymphoma associated stromal cells as an innovative therapeutic target for diffuse large B cell lymphoma

01.09.2022      

Sabrina Kalmbach , Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart
Global profiling of localized and systemic forms of follicular lymphoma: the relevance of molecular features in different clinical stages

22.09.2022      

Julia Thiel , Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart
The interplay between the tumo rmicroenvironment and drug therapy in precision-cut tissue slices

06.10.2022      

Selina Maier , Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart
Anti-hormone therapy affects BKCa channel dependent K+ homeostasis in murine and human breast cancer cells

19.10.2022      

Prof. Hiltrud Brauch , Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart
How to write a paper for scientific publishing

27.10.2022      

Lena Sophie Menig , Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart
Heterogeneity of monocarboxylate transporter 1 and 4 (MCT1/MCT4) in clear cell renal cell carcinoma (ccRCC) and metastasis

23.11.2022      

Dr. Maaike van der Lee , Department of Clinical Pharmacy and Toxicology Leiden University Medical Centre
Long read sequencing and AI in pharmacogenomics

30.11.2022      

Prof. Dr. Albert Braeuning , German Federal Institute for Risk Assessment
Food safety at the German Federal Institute for Risk Assessment

 

Due to the Corona Pandemic lectures were still limited. 

 

16.06.2021      

Prof. Jörg Albert, MD, Robert Bosch Hospital, Stuttgart
Physiology and pathophysiology of the gastrointestinal tract

30.06.2021   

Christian Schäfer, MD, Robert Bosch Hospital, Stuttgart
Physiology and pathophysiology of the liver 

08.12.2021   

Prof. Olaf Rieß, MD, University Hospital, Tuebingen
Diagnostics of Rare Diseases: Beyond The Exome 

 

Due to the Corona Pandemic there were no lectures.

06.02.2019      

Prof. Uwe Fuhr, MD, University Hospital of the University of Cologne(BfR)
Pharmacokinetics

01.03.2019   

Prof. Volker Lauschke, PhD, Karolinska Institute, Stockholm
Inter-individual Differences in Drug Response - From Computational Predictions to Experimental Models 

05.06.2019   

Prof. Thomas Wider, MD, University Medical Center Tübingen
Immune Senescence Surveillance of Tumours 

10.07.2019      

Prof. German Ott, MD, Robert Bosch Hospital, Stuttgart
Diagnostic Pathology: A Method Bridging Classical Morphology and Molecular Genetics

17.07.20191   

Prof. Michael Schwarz, MD, University Hospital Tübingen
Mechanisms of Tumor Promotion  

06.11.2019   

Christina Justenhoven, PhD, Bioscientia - Institute of Medical Diagnostic GmbH, Ingelheim
Analysis of DNA variations  

20.11.2019   

Prof. Marius Üffing, PhD, University Tübingen
Proteomics - From basic approaches to clinical applications  

 

24.01.2018      

Prof. Albert Bräuning, PhD, German Federal Institute for Risk Assessment (BfR)
Food Safety at the German Federal Institute for Risk Assessments

17.10.2018   

Prof. Uwe Fuhr, MD, University Hospital of the University of Cologne
Pharmacokinetics - Basic Principles  

05.12.2018   

Prof. Klaus Mörike, MD, University Hospital Tübingen
Clinical Studies – Design and Realization 

06.12.2018      

Pavel Bashtrykov, PhD, University Stuttgart
Epigenetic silencing of oncogenes: a novel approach for targeted cancer therapy

 

24.05.2017      

Prof. Joerg Albert, MD, Robert Bosch Hospital
Physiology and pathophysiology of the digestive system

31.05.2017   

Christian Schäfer, MD, Robert Bosch Hospital
Physiology and pathophysiology of the liver  

31.05.2017   

Prof. Jun J. Yang, Ph.D., St. Jude Children's Research Hospital
Pharmacogenomics of Thiopurines and Precision Medicine: From Genomics to Clinical Actions 

14.06.2017      

Prof. Godehard Friedel, MD, Robert Bosch Hospital - Schillerhoehe
Physiology and pathophysiology of the lungs

21.06.2017      

Prof. Andreas Hartkopf, MD, University Hospital Tuebingen)
Physiology and pathophysiology of the breast

28.06.2017   

Prof. Kilian Rapp, MD, Robert Bosch Hospital
Physiological Specialties in Elderly Patients  

05.07.2017   

Prof. Peter Ong, MD, Robert Bosch Hospital
Physiology and pathophysiology of the cardiovascular System  

13.07.2017      

Prof. Robert Feil, PhD, University of Tuebingen
Seeing is believing: Combining biochemistry and mouse genetics to visualize physiology, pathophysiology and pharmacology

12.07.2017      

Martin Kimmel, MD, Robert Bosch Hospital
Physiology and pathophysiology of the kidneys

19.07.2017   

Prof. Andreas Nüssler, MD, University of Tuebingenm
Cell culture approaches towards 3D micro-organ Engineering  

18.09.2017   

Prof. Sven Glaesker, MD, University Hospital Brussels
Molecular and morphological pathogenesis in von Hippel-Lindau (VHL) disease 

08.11.2017      

Prof. Klaus Moerike, MD, University Hospital Tuebingen
Arzneimitteltherapie kardialer Arrhythmien

15.11.2017      

Prof. Robert Lukowski, PhD, University Hospital Tuebingen
The NO-cGMP system: Implications for disease biology and therapy

22.11.2017   

Reinhold Kerb, MD, CRS Clinical Research GmbHm
Drug Therapy of Diabetes, Obesity, Metabolic Syndrome  

29.11.2017   

Prof. Peter Muenzel, University of Tuebingen
Gifte und Vergiftungen  

08.12.2017      

Prof. Carsten Gruellich, MD, NCT -National Center for Tumor Diseases Heidelberg Medical Oncology
Molekulare Heterogenität und therapiegetriebene Evolution des Nierenzellkarzinoms

11.12.2017      

Markus Morkel, MD, Charité - University Hospital Berlin
Organoids as a tool to assess oncogene characteristics and cancer signaling networks

13.12.2017   

Prof. Robert Juette, PhD, Institute of the History of Medicine, Robert Bosch Stiftung
Der Placebo Effekt: Past and Present  

 

BOGY 2024

  • 18th  March to 22nd March, 2024
  • 22nd April to 26th April, 2024

For availabilites, please contact us on sekretariat@ikp-stuttgart.de